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The Origin of Life

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Protein Prebiotic Synthesis

Synthesizing proteins under prebiotic conditions is not as straight forward as many would have predicted. Ten (maybe 12) of the amino acids are relatively easy to create. Both L and D isomers are created, and two amino acids alanine and glycine almost always dominate the mixture. Despite these issues, creating the amino acids is not that difficult. It is forcing the amino acids to form peptide bonds that is difficult.

Miller’s Spark Experiment


Figure 9.5 illustrates the Miller spark chamber. The water in the flask is boiling. The atmosphere above the water and in the spark chamber is controlled. In this example, hydrogen, methane and ammonia are introduced. The electrode is charged to a very high voltage, and it creates an electric spark. This spark is an energy source. It allows the chemicals in the chamber to react and form new chemicals. The condenser removes the chemicals from the spark chamber, and they accumulate in the trap. Life uses 20 amino acids. Miller’s chamber can create between 0 and 10 of the 20 ( the number created depends on the gases used in the atmosphere).

   The chamber also creates many other chemicals. Other scientists have repeated this experiment with alternative energy sources like UV light and heat. These experiments demonstrate that many amino acids are easy to create. Miller’s chamber is a non-equilibrium system cleverly designed and optimized to create nonvolatile organic compounds like amino acids.

   Whether or not this experiment is representative of the conditions on the early earth is questionable. Many scientists today do not believe that ammonia, hydrogen and methane were present in the earth’s early atmosphere, and without at least one of these, no amino acids are produced by the spark chamber. Despite these concerns, Miller's experiment remains to this day the greatest accomplishment in origins research.


Figure 9.5: Miller’s Chamber


miller-spark-chamber.GIF (20320 bytes)


             

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